Why do you want to kill the game?

I think systems like Runescape's prayer + potions + food system or SWG's foodstuffs + doctor and entertainer buffs system are great examples. Both systems still have depth in how weapons or armor are made and can be stronger but most of the buffing and items are prepped and used ahead of combat. With the only active bits I remember being prayer swapping in RS and using damage mitigation food in SWG but both of those had limited uses per combat.